Appropriate indicated use for IVIG in neonatal infections

Ying Wang, Yi Ping Liu, Hai Yan Yuan, Yi Wen Xiao, Xu Ping, Tao Bo

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Infection is a leading cause of mortality and morbidity in the newborn and preterm neonates due to immuno-incompetence in these patients. Administration of intravenous immunoglobulin (IVIG) provides immunoglobulin G (IgG) that can protect the body from infection. In theory, morbidity and mortality due to infections in newborns and preterms infants could be reduced by the administration of IVIG. Two meta-analyses were evaluated comparing IVIG to treat various infection verses conventional treatments. The results showed IVIG is not effective as an adjunctive treatment for suspected or proven infections in neonates.


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Copyright (c) 2016 Ying Wang, Yi Ping Liu, Hai Yan Yuan, Yi Wen Xiao, Xu Ping, Tao Bo

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