Respiratory Exacerbations and their Association with Particulate Matter Fluctuations at Hugo Mendoza Pediatric Hospital

Authors

Keywords:

Disease exacerbation, Respiration disorders, Particulate matter, association, pediatric hospital

Abstract

Introduction: Millions of children are exposed daily to air pollution, one of whose components is particulate matter, which is especially harmful to the pediatric population and can worsen the course of respiratory diseases.

Objective: To describe the association between respiratory disease exacerbations and particulate matter fluctuations at the Dr. Hugo Mendoza Pediatric Hospital, between 2017 and 2022.

Methods: An observational, analytical and longitudinal study was conducted using secondary data. The study population comprised 344 670 patients, with a sample size of 56 734 cases. A Poisson regression was performed to analyze the association between exacerbations of respiratory disease and particulate matter concentration.

Results: The findings indicated that the predominant respiratory exacerbation was bronchial asthma, mainly affecting children aged 1-2 years, mostly males. It was shown that for each unit increase in the average concentration of fine particulate matter and coarse particulate matter, exacerbations of respiratory diseases increased by 4,7% and 3,0%, respectively.

Conclusions: Bronchial asthma was the predominant disease with respiratory exacerbations, and a higher average concentration of particulate matter was significantly related to an increase in the number of respiratory exacerbations. These findings could have implications for a better understanding of the relationship between exposure to particulate matter and the frequency of respiratory exacerbations in our context, suggesting the need for environmental prevention and control measures to mitigate adverse effects on respiratory health.

Downloads

Download data is not yet available.

Author Biographies

Alarice Aysset Francisco Acevedo, Instituto de Investigación en Salud (INSIS), Universidad Autónoma de Santo Domingo

MD, Health Research Fellowship

Miguel Gallego Munuera, Escuela Nacional de Sanidad, Instituto de Salud Carlos III, Madrid

MD, Master of Public Health

Anderson Emmanuel Tavarez Gonzalez, Instituto de Investigación en Salud (INSIS), Universidad Autónoma de Santo Domingo

MD, Health Research Fellowship

References

1. Ubilla C, Yohannessen K. Outdoor air pollution and asthma in children. Neumol Pediatr. 2021 [access 05/07/2024];16(4):164-6. Available from: https://www.researchgate.net/publication/357112506_CONTAMINACION_ATMOSFERICA_Y_ASMA_EN_NINOS

2. Zhang W, Ling J, Zhang R, Dong J, Zhang L, Chen R, et al. Short-term effects of air pollution on hospitalization for acute lower respiratory infections in children: a time-series analysis study from Lazhou, China. BMC Public Health. 2023 [access 05/07/2024];23:1629. Available from: https://pubmed.ncbi.nlm.nih.gov/37626307/#:~:text=Conclusions%3A%20PM2.5%2C%20PM10,rates%20for%20childhood%20respiratory%20diseases

3. Adhikary M, Mal P, Saikia N. Exploring the link between particulate matter pollution and acute respiratory infection risk in children using generalized estimating equations analysis: a robust statistical approach. BMC Public Health. 2024 [access 05/07/2024];23:12. Available from: https://pubmed.ncbi.nlm.nih.gov/38273338/

4. Ziou M, Tham R, Wheeler AJ, Zosky GR, Stephens N, Johnston FH. Outdoor particulate matter exposure and upper respiratory tract infections in children and adolescents: A systematic review and meta-analysis. Environ. Res. 2024 [access 05/07/2024];210:112969. Available from: https://pubmed.ncbi.nlm.nih.gov/35183515/

5. Air pollution. Children’s Environmental Health Collaborative; s. a. [acces 11/07/2024]. Available from: https://ceh.unicef.org/spotlight-risk/air-pollution

6. Cifuentes Martínez P, Rodríguez-Fernández A, Luengo C, Tapia L. Relationship between air pollution and respiratory disease consultations in primary emergency care. Rev Chil Enferm Respir. 2020 [accesos05/07/2024];36(1):260-7. Available from: https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-73482020000400260

7. Dondi A, Carbone C, Manieri E, Zama D, Del Bono C, Betti L, et al. Outdoor Air Pollution and Childhood Respiratory Disease: The Role Of Oxidative Stress. Int J Mol Sci. 2023 [access 05/07/2024];24(5):4345. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10001616/

8. Household air pollution. Who.int. [acceso 06/07/2024]. Disponible en: https://www.who.int/en/news-room/fact-sheets/detail/household-air-pollution-and-health

9. Young Kyung S, Hwan Jeong S. Particulate-Matter Related Respiratory Diseases. Tuberc Respir Dis. 2020 [access 06/07/2024];83(1):116-21. Available from: https://pubmed.ncbi.nlm.nih.gov/32185911/

10. Diario Libre. Salud Pública emite alerta epidemiológica por circulación de varios virus respiratorios. Diario Libre; 2023 [access 07/07/2024]. Available from: https://www.diariolibre.com/actualidad/salud/2023/12/25/salud-publica-emite-alerta-epidemiologica-por-virus-respiratorios/2560581

11. Pantaleón D. El país está ante una oleada de enfermedades respiratorias. listindiario.com; 2023 [access 08/07/2024]. Available from: https://listindiario.com/la-republica/sector-salud/20230929/pais-esta-oleada-enfermedades-respiratorias_775158.html

12. Datos abiertos – Hospital Pediátrico Dr. Hugo Mendoza. Gob.do; s. a. [access 08/07/2024]. Available from: https://hospitalhugomendoza.gob.do/transparencia/datos-abiertos/

13. Oficina Nacional de Estadística (ONE). Condiciones Físicas y Calidad Ambiental - Oficina Nacional de Estadística (ONE). Oficina Nacional de Estadística (ONE); s. a. [access 04/07/2024]. Available from: https://www.one.gob.do/datos-y-estadisticas/temas/estadisticas-ambientales-y-de-cambio-climatico/condiciones-fisicas-y-calidad-ambiental/

14. Zhang Y, Yin X, Zheng X. The relationship between PM2.5 and the onset and exacerbation of childhood asthma: a short communication. Front. Pediatr. 2023 [access 15/07/2024];11(1):1-6. Available from: https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1191852/full

15. López Y. Incendios forestales en RD: “Hemos mejorado mucho la capacidad de respuesta”. listindiario.com; 2022 [access 17/07/2024]. Available from: https://listindiario.com/la-vida/2022/02/24/710301/incendios-forestales-en-rd-hemos-mejorado-mucho-la-capacidad-de-respuesta_171652.html

16. Redacción CDN. Nube de polvo del Sahara llega a República Dominicana. cdn.com.do; s. a. [access 18/07/2024]. Available from: https://cdn.com.do/principales/nube-de-polvo-del-sahara-llega-a-republica-dominicana/

17. Listín Diario. Polvo del Sahara eleva las temperaturas hasta 35 grados; pero la sensación térmica podría ser de 40. listindiario.com; 2021 [access 19/07/2024]. Available from: https://listindiario.com/la-republica/2021/08/30/686081/polvo-del-sahara-eleva-las-temperaturas-hasta-35-grados-pero-la-sensacion-termica-podria-ser-de-40.html

18. Remaggi J, Mardones C, Jiménez J. Impact of pollution by particulate matter on emergency room admissions for respiratory causes in Chillán, Concepción, and Los Ángeles, Chile. Rev Chil Enferm Respir. 2019 [accesss 05/07/2024];35:181-90. Available from: https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-73482019000300181

Published

2026-02-15

How to Cite

1.
Francisco Acevedo AA, Gallego Munuera M, Tavarez Gonzalez AE. Respiratory Exacerbations and their Association with Particulate Matter Fluctuations at Hugo Mendoza Pediatric Hospital. Rev Cubana Pediatría [Internet]. 2026 Feb. 15 [cited 2026 Mar. 2];98. Available from: https://revpediatria.sld.cu/index.php/ped/article/view/7806