First outbreak of COVID-19 in Cuban pediatric patients

Authors

  • Maidalys Bravo Ramírez Centro Nacional de Genética Médica
  • Estela Morales Peralta
  • Yaíma Zúñiga Rosales
  • Hilda Roblejo Balbuena
  • María de los Ángeles González Torres
  • Yudelmis Álvarez Gavilán
  • Yudelkis Benítez Cordero
  • Giselle Monzón Benítez
  • Nayade Pereira Roche
  • Beatriz Marcheco Teruel

Keywords:

SARS-CoV-2, pediatric patients, Cuba.

Abstract

Introduction: Until June 11, 2020, 10.4% of the total positive cases of SARS-CoV-2 in Cuba corresponded to patients under 18 years of age. Clinical manifestations in children affected by SARS-CoV-2 are usually mild and few deaths occur compared to other age groups.

Objective: Characterize from the clinical, epidemiological and immunological point of view the Cuban pediatric patients infected by SARS-CoV-2 until June 11, 2020.

Methods: Observational, cross-sectional study in 137 pediatric patients infected with COVID-19, who were epidemiologically discharged.

Results: 56.9 % of the patients presented asymptomatic form of the disease. Havana was the most affected province and the average age was 11.3 years. The most frequent symptoms were: fever, cough and diarrhea and occurred more frequently in patients with black skin (Odd Ratio = 3.40). Antibody concentrations for tetanus and Haemophilus influenzae type b provided protection in 92.7% to 100% of children, while for diphtheria 24.8% had no reliable protection. Of the symptomatic patients, 62.5% developed specific total antibodies against SARS-CoV-2.

Conclusions: Patients in pediatric ages can contribute significantly to the transmission dynamics. Reliable protection for specific vaccines, the development of total antibodies to SAR-Cov-2, and general favorable prognosis without complications require continued research to identify biological and immunological differences between children and other age groups.

 

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Author Biography

Maidalys Bravo Ramírez, Centro Nacional de Genética Médica

especialista en Genética Clínica. Área de atención médica del Centro Nacional de Genética Médica.

Published

2021-11-04

How to Cite

1.
Bravo Ramírez M, Morales Peralta E, Zúñiga Rosales Y, Roblejo Balbuena H, González Torres M de los Ángeles, Álvarez Gavilán Y, et al. First outbreak of COVID-19 in Cuban pediatric patients. Rev Cubana Pediatría [Internet]. 2021 Nov. 4 [cited 2025 Jun. 29];93. Available from: https://revpediatria.sld.cu/index.php/ped/article/view/1514