Clinical and epidemiological features of the covid-19 in children
Keywords:
children, COVID-19, clinical and epidemiological features.Abstract
Introduction: The COVID-19 pandemic determines the relevance of the analysis of clinical and epidemiological features in various periods of the rise in morbidity among the child population.
Objective: To study of the clinical and epidemiological features of the COVID-19 in children.
Methods: The analysis of medical documents of 585 patients aged from 1 month to 17 years who were under the supervision of the district pediatric service of the city children's polyclinics in Ryazan for the period from March 2020 to December 2021 with a verified diagnosis: new coronavirus infection.
Results: There was a predominance of school-age children (68.7%). Contamination of SARS-CoV-2 most often occurred as a result of other family members (87.2%). In most cases, a mild course of the disease was noted (71.8%). Premorbid conditions was detected in 8.4% of children, it was 10.7 times more often recorded in children with a moderate course of the disease (p<0.001). The symptoms of intoxication (74.9%) and respiratory tract damage (69.6%) were dominated in the clinical happening of COVID-19. Gastrointestinal manifestations were more common in children of 0 to 7 years old (p<0.001), dysosmia and dysgeusia – in school-age children (p<0.001).
Conclusion: In most of the examined children, COVID-19 proceeded in a mild form. Correlations were found between the severity of the new coronavirus infection and the presence of concomitant pathology, as well as between the age of patients and the presence of gastrointestinal symptoms, dysgeusia and dysosmia. Postcovidsyndrome were noted infrecuently; in most cases they manifested as symptoms of asthenia.
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1. Jackson G. COVID-19 and socio-economics. Socio-Economic Review. 2021 [accessed 21/07/2021];19(1):1-6. Available in: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344671/
2. Johns Hopkins University & Medicine. Coronavirus Resource Center. COVID-19 data in motion. [accessed 22/11/2022]. Available in:
https://coronavirus.jhu.edu/covid-19-daily-video
3. Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 Among Children in China. Pediatrics. 2020 [accessed 16/03/2020];145(6):e20200702. Available in: https://publications.aap.org/pediatrics/article/145/6/e20200702/76952/Epidemiology-of-COVID-19-Among-Children-in-China
4. Belyh NA, Solov'eva OA, Anikeeva NA. Epidemiological and clinical and laboratory features of COVID-19 in pediatric patients. Pediatrician.2021;12(6):63-76. Available in: https://journals.rcsi.science/pediatr/article/view/106325
5. Toba N, Gupta S, Ali AY, ElSaban M, Khamis AH, Ho SB, et al.COVID-19 under 19: A meta-analysis. Pediatr Pulmonol. 2021;56(6):1332-1341. DOI: 10.1002/ppul.25312
6. Ministry of Health of the Russian Federation. Interim guidelines «Prevention, diagnosis and treatment of new coronavirus infection (COVID-19)». Version 15 (22/02/2022) [accessed 22/11/2022]. Available in: https://static-0.minzdrav.gov.ru›system…COVID-19_V15.pdf .
7. Maltezou HC, Magaziotou I, Dedoukou X, Eleftheriou E, Raftopoulos V, Michos A, et al. Children and Adolescents With SARS-CoV-2 Infection: Epidemiology, Clinical Course and Viral Loads. Pediatr Infect Dis J. 2020 [accessed 01/12/2020];39(12):e388-e392. Available in: https://journals.lww.com/pidj/fulltext/2020/12000/children_and_adolescents_with_sars_cov_2.1.aspx
8. Centers for Disease Control and Prevention. COVID Data Tracker. Cases, Deathes and Testing. 2022 [accessed 22/11/2022]. Available in: https://covid.cdc.gov/covid-data-tracker/#demographics
9. Couture A, Lyons BC, Mehrotra ML, Sosa L, Ezike N, Ahmed FS, et al. Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence and Reported Coronavirus Disease 2019 Cases in US Children, August 2020-May 2021. Open Forum Infect Dis. 2022 [accessed 01/01/2022];9(3):ofac044. Available in: https://academic.oup.com/ofid/article/9/3/ofac044/6517552?login=false
10. Havers FP, Reed C, Lim T, Montgomery JM, Klena JD, Hall AJ, et al. Seroprevalence of Antibodies to SARS-CoV-2 in 10 Sites in the United States, March 23-May 12, 2020. JAMA Intern Med. 2020 [accessed 21/07/2021];7:1576-1586. Available in: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2768834
11. COVID-19: Clinical manifestations and diagnosis in children. [accessed 22/11/2022]. Available in: https://www.uptodate.com/contents/covid-19-clinical-manifestations-and-diagnosis-inchildren?topicRef=127759&source=see_link
12. Grijalva CG, Rolfes MA, Zhu Y, McLean HQ, Hanson KE, Belongia EA, et al. Transmission of SARS-COV-2 Infections in Households - Tennessee and Wisconsin, April-September 2020. MMWR Morb Mortal Wkly Rep. 2020; [accessed 06/11/2020];69:1631-4. Available in: https://www.cdc.gov/mmwr/volumes/69/wr/mm6944e1.htm?s_cid=mm6944e1_w
13. Macartney K, Quinn HE, Pillsbury AJ, Koirala A, Deng L, Winkler N, et al. Transmission of SARS-CoV-2 in Australian educational settings: a prospective cohort study. Lancet Child Adolesc Health. 2020 [accessed 02/11/2020];4(11):807-16. Available in: https://www.scirp.org/reference/referencespapers.aspx?referenceid=3554052
14. Vivanti AJ, Vauloup-Fellous C, Prevot S, Zupan V, Suffee C, Do Cao J, et al. Transplacental transmission of SARS-CoV-2 infection. Nat Commun. 2020 [accessed 14/07/2020];11(1):3572. Available in: https://www.nature.com/articles/s41467-020-17436-6
15. Ministry of Health of the Russian Federation. Temporary guidelines «Prevention, diagnosis and treatment of new coronavirus infection (COVID-19)». Version 14 (27/12/2021) Russian; 2021 [accessed 27/12/2021]. Available in: https://pravo.ppt.ru/vremennyye-metodicheskiyerekomendatsii/260143?ysclid=lmelv29dkf761973012
16. Bondarenko A. L. Features of the course of COVID-19 in children undergoing outpatient treatment. Children's Infections. 2022 [accessed 27/06/2022];21(3):18-21. Available in: https://detinf.elpub.ru/jour/article/view/748
17. Ng DC, Tan KK, Chin L, Ali MM, Lee ML, Mahmood FM, et al. Clinical and epidemiological characteristics of children with COVID-19 in Negeri Sembilan, Malaysia. Int J Infect Dis. 2021 [accessed 01/06/2021];108:347-352. Available in: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168297/
18. Sarangi B, Reddy VS, Oswal JS, Malshe N, Patil A, Chakraborty M, et al. Epidemiological and Clinical Characteristics of COVID-19 in Indian Children in the Initial Phase of the Pandemic. Indian Pediatr. 2020 [accessed 15/10/2020];57(10):914-917. Available in: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605483/
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