Iron deficiency anemia as a risk factor for the onset of the first simple febrile crisis

Authors

Keywords:

simple febrile crisis, iron deficiency anemia, children.

Abstract

Introduction: Among the factors that can increase the risk of febrile crisis is iron deficiency anemia, although there are studies with contradictory results.

Objective: Determine the role of iron deficiency anemia as a risk factor for the first simple febrile crisis.

Methods: Prospective case-control study, conducted from January to December 2019, at the Huacho-Lima Regional Hospital, Peru, in 102 children aged 6 to 60 months. Patients were divided into 2 groups: the group of cases with simple febrile crisis and the control group with fever without crisis. Iron deficiency anemia was defined with hematological indicators such as hemoglobin<11 g/dl, mean corpuscular volume< 70 fl and erythrocyte distribution width > 15%. The definition of febrile crisis was according to the American Academy of Pediatrics.

Results: 68.6 % of iron deficiency anemia was found in the case group against 37.3 % in the control group (p = 0.0029). Hemoglobin and mean corpuscular volume had lower mean values in cases compared to the control group (p= 0.002). The erythrocyte distribution width was higher in cases compared to the control group (p=0.006). The crude odds ratio between iron deficiency anemia and the first febrile crisis was 3.684 (95% CI: 1.622-8.363; p= 0.002) and OR adjusted by simple binary logistic regression of 1.699 (95% CI: 1.191-2.423; p=0.003).

Conclusions: Iron deficiency´s anemia is a risk factor for the first simple febrile crisis.

 

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Author Biography

oreste Basombrio Contreras, Universidad Nacional de Barranca

Médico pediatra del servicio de pediatria del Hospital Regional Huacho Lima - Peru

Published

2021-10-01

How to Cite

1.
Basombrio Contreras oreste, Lam Figueroa NM. Iron deficiency anemia as a risk factor for the onset of the first simple febrile crisis. Rev Cubana Pediatría [Internet]. 2021 Oct. 1 [cited 2025 Jul. 3];93(4). Available from: https://revpediatria.sld.cu/index.php/ped/article/view/1409

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